Búsqueda | Portal de Búsqueda de la BVS Ecuador

1.

Genomics of Immune Diseases and New Therapies.

Lenardo, Michael; Lo, Bernice; Lucas, Carrie L.

Annu Rev Immunol ; 34: 121-49, 2016 05 20.

Artículo en Inglés | MEDLINE | ID: mdl-26735698

2.

Mucus sialylation determines intestinal host-commensal homeostasis.

Yao, Yikun; Kim, Girak; Shafer, Samantha; Chen, Zuojia; Kubo, Satoshi; Ji, Yanlong; Luo, Jialie; Yang, Weiming; Perner, Sebastian P; Kanellopoulou, Chrysi; Park, Ann Y; Jiang, Ping; Li, Jian; Baris, Safa; Aydiner, Elif Karakoc; Ertem, Deniz; Mulder, Daniel J; Warner, Neil; Griffiths, Anne M; Topf-Olivestone, Chani; Kori, Michal; Werner, Lael; Ouahed, Jodie; Field, Michael; Liu, Chengyu; Schwarz, Benjamin; Bosio, Catharine M; Ganesan, Sundar; Song, Jian; Urlaub, Henning; Oellerich, Thomas; Malaker, Stacy A; Zheng, Lixin; Bertozzi, Carolyn R; Zhang, Yu; Matthews, Helen; Montgomery, Will; Shih, Han-Yu; Jiang, Jiansheng; Jones, Marcus; Baras, Aris; Shuldiner, Alan; Gonzaga-Jauregui, Claudia; Snapper, Scott B; Muise, Aleixo M; Shouval, Dror S; Ozen, Ahmet; Pan, Kuan-Ting; Wu, Chuan; Lenardo, Michael J.

Cell ; 185(7): 1172-1188.e28, 2022 03 31.

Artículo en Inglés | MEDLINE | ID: mdl-35303419

3.

Congenital iRHOM2 deficiency causes ADAM17 dysfunction and environmentally directed immunodysregulatory disease.

Kubo, Satoshi; Fritz, Jill M; Raquer-McKay, Hayley M; Kataria, Rhea; Vujkovic-Cvijin, Ivan; Al-Shaibi, Ahmad; Yao, Yikun; Zheng, Lixin; Zou, Juan; Waldman, Alex D; Jing, Xinyi; Farley, Taylor K; Park, Ann Y; Oler, Andrew J; Charles, Adrian K; Makhlouf, Melanie; AbouMoussa, Eman H; Hasnah, Reem; Saraiva, Luis R; Ganesan, Sundar; Al-Subaiey, Abdulrahman Ahmed; Matthews, Helen; Flano, Emilio; Lee, Hyun Hee; Freeman, Alexandra F; Sefer, Asena Pinar; Sayar, Ersin; Çakir, Erkan; Karakoc-Aydiner, Elif; Baris, Safa; Belkaid, Yasmine; Ozen, Ahmet; Lo, Bernice; Lenardo, Michael J.

Nat Immunol ; 23(1): 75-85, 2022 01.

Artículo en Inglés | MEDLINE | ID: mdl-34937930

4.

Broadly effective metabolic and immune recovery with C5 inhibition in CHAPLE disease.

Ozen, Ahmet; Kasap, Nurhan; Vujkovic-Cvijin, Ivan; Apps, Richard; Cheung, Foo; Karakoc-Aydiner, Elif; Akkelle, Bilge; Sari, Sinan; Tutar, Engin; Ozcay, Figen; Uygun, Dilara Kocacik; Islek, Ali; Akgun, Gamze; Selcuk, Merve; Sezer, Oya Balci; Zhang, Yu; Kutluk, Gunsel; Topal, Erdem; Sayar, Ersin; Celikel, Cigdem; Houwen, Roderick H J; Bingol, Aysen; Ogulur, Ismail; Eltan, Sevgi Bilgic; Snow, Andrew L; Lake, Camille; Fantoni, Giovanna; Alba, Camille; Sellers, Brian; Chauvin, Samuel D; Dalgard, Clifton L; Harari, Olivier; Ni, Yan G; Wang, Ming-Dauh; Devalaraja-Narashimha, Kishor; Subramanian, Poorani; Ergelen, Rabia; Artan, Reha; Guner, Sukru Nail; Dalgic, Buket; Tsang, John; Belkaid, Yasmine; Ertem, Deniz; Baris, Safa; Lenardo, Michael J.

Nat Immunol ; 22(2): 128-139, 2021 02.

Artículo en Inglés | MEDLINE | ID: mdl-33398182

5.

30 Years of NF-κB: A Blossoming of Relevance to Human Pathobiology.

Zhang, Qian; Lenardo, Michael J; Baltimore, David.

Cell ; 168(1-2): 37-57, 2017 Jan 12.

Artículo en Inglés | MEDLINE | ID: mdl-28086098

6.

BACH2 immunodeficiency illustrates an association between super-enhancers and haploinsufficiency.

Afzali, Behdad; Grönholm, Juha; Vandrovcova, Jana; O'Brien, Charlotte; Sun, Hong-Wei; Vanderleyden, Ine; Davis, Fred P; Khoder, Ahmad; Zhang, Yu; Hegazy, Ahmed N; Villarino, Alejandro V; Palmer, Ira W; Kaufman, Joshua; Watts, Norman R; Kazemian, Majid; Kamenyeva, Olena; Keith, Julia; Sayed, Anwar; Kasperaviciute, Dalia; Mueller, Michael; Hughes, Jason D; Fuss, Ivan J; Sadiyah, Mohammed F; Montgomery-Recht, Kim; McElwee, Joshua; Restifo, Nicholas P; Strober, Warren; Linterman, Michelle A; Wingfield, Paul T; Uhlig, Holm H; Roychoudhuri, Rahul; Aitman, Timothy J; Kelleher, Peter; Lenardo, Michael J; O'Shea, John J; Cooper, Nichola; Laurence, Arian D J.

Nat Immunol ; 18(7): 813-823, 2017 Jul.

Artículo en Inglés | MEDLINE | ID: mdl-28530713

7.

Dual proteolytic pathways govern glycolysis and immune competence.

Lu, Wei; Zhang, Yu; McDonald, David O; Jing, Huie; Carroll, Bernadette; Robertson, Nic; Zhang, Qian; Griffin, Helen; Sanderson, Sharon; Lakey, Jeremy H; Morgan, Neil V; Reynard, Louise N; Zheng, Lixin; Murdock, Heardley M; Turvey, Stuart E; Hackett, Scott J; Prestidge, Tim; Hall, Julie M; Cant, Andrew J; Matthews, Helen F; Koref, Mauro F Santibanez; Simon, Anna Katharina; Korolchuk, Viktor I; Lenardo, Michael J; Hambleton, Sophie; Su, Helen C.

Cell ; 159(7): 1578-90, 2014 Dec 18.

Artículo en Inglés | MEDLINE | ID: mdl-25525876

8.

Dominant-activating germline mutations in the gene encoding the PI(3)K catalytic subunit p110Î´ result in T cell senescence and human immunodeficiency.

Lucas, Carrie L; Kuehn, Hye Sun; Zhao, Fang; Niemela, Julie E; Deenick, Elissa K; Palendira, Umaimainthan; Avery, Danielle T; Moens, Leen; Cannons, Jennifer L; Biancalana, Matthew; Stoddard, Jennifer; Ouyang, Weiming; Frucht, David M; Rao, V Koneti; Atkinson, T Prescott; Agharahimi, Anahita; Hussey, Ashleigh A; Folio, Les R; Olivier, Kenneth N; Fleisher, Thomas A; Pittaluga, Stefania; Holland, Steven M; Cohen, Jeffrey I; Oliveira, Joao B; Tangye, Stuart G; Schwartzberg, Pamela L; Lenardo, Michael J; Uzel, Gulbu.

Nat Immunol ; 15(1): 88-97, 2014 Jan.

Artículo en Inglés | MEDLINE | ID: mdl-24165795

9.

Mutations that prevent caspase cleavage of RIPK1 cause autoinflammatory disease.

Lalaoui, Najoua; Boyden, Steven E; Oda, Hirotsugu; Wood, Geryl M; Stone, Deborah L; Chau, Diep; Liu, Lin; Stoffels, Monique; Kratina, Tobias; Lawlor, Kate E; Zaal, Kristien J M; Hoffmann, Patrycja M; Etemadi, Nima; Shield-Artin, Kristy; Biben, Christine; Tsai, Wanxia Li; Blake, Mary D; Kuehn, Hye Sun; Yang, Dan; Anderton, Holly; Silke, Natasha; Wachsmuth, Laurens; Zheng, Lixin; Moura, Natalia Sampaio; Beck, David B; Gutierrez-Cruz, Gustavo; Ombrello, Amanda K; Pinto-Patarroyo, Gineth P; Kueh, Andrew J; Herold, Marco J; Hall, Cathrine; Wang, Hongying; Chae, Jae Jin; Dmitrieva, Natalia I; McKenzie, Mark; Light, Amanda; Barham, Beverly K; Jones, Anne; Romeo, Tina M; Zhou, Qing; Aksentijevich, Ivona; Mullikin, James C; Gross, Andrew J; Shum, Anthony K; Hawkins, Edwin D; Masters, Seth L; Lenardo, Michael J; Boehm, Manfred; Rosenzweig, Sergio D; Pasparakis, Manolis.

Nature ; 577(7788): 103-108, 2020 01.

Artículo en Inglés | MEDLINE | ID: mdl-31827281

10.

Evaluating the efficacy and safety of pozelimab in patients with CD55 deficiency with hyperactivation of complement, angiopathic thrombosis, and protein-losing enteropathy disease: an open-label phase 2 and 3 study.

Ozen, Ahmet; Chongsrisawat, Voranush; Sefer, Asena Pinar; Kolukisa, Burcu; Jalbert, Jessica J; Meagher, Karoline A; Brackin, Taylor; Feldman, Hagit Baris; Baris, Safa; Karakoc-Aydiner, Elif; Ergelen, Rabia; Fuss, Ivan J; Moorman, Heather; Suratannon, Narissara; Suphapeetiporn, Kanya; Perlee, Lorah; Harari, Olivier A; Yancopoulos, George D; Lenardo, Michael J.

Lancet ; 403(10427): 645-656, 2024 Feb 17.

Artículo en Inglés | MEDLINE | ID: mdl-38278170

11.

A randomized, placebo-controlled phase 3 trial of the PI3KÎ´ inhibitor leniolisib for activated PI3KÎ´ syndrome.

Rao, V Koneti; Webster, Sharon; Sedivá, Anna; Plebani, Alessandro; Schuetz, Catharina; Shcherbina, Anna; Conlon, Niall; Coulter, Tanya; Dalm, Virgil A; Trizzino, Antonino; Zharankova, Yulia; Kulm, Elaine; Körholz, Julia; Lougaris, Vassilios; Rodina, Yulia; Radford, Kath; Bradt, Jason; Kucher, Klaus; Relan, Anurag; Holland, Steven M; Lenardo, Michael J; Uzel, Gulbu.

Blood ; 141(9): 971-983, 2023 03 02.

Artículo en Inglés | MEDLINE | ID: mdl-36399712

12.

Ulrich Siebenlist (1951-2020).

Murphy, Philip M; Lenardo, Michael J.

Immunity ; 54(3): 391-392, 2021 Mar 09.

Artículo en Inglés | MEDLINE | ID: mdl-33691124

13.

Early B cell factor 4 modulates FAS-mediated apoptosis and promotes cytotoxic function in human immune cells.

Kubo, Satoshi; Kataria, Rhea; Yao, Yikun; Gabrielski, Justin Q; Zheng, Lixin; Markowitz, Tovah E; Chan, Waipan; Song, Jian; Boddapati, Arun K; Saeki, Keita; Häupl, Björn; Park, Ann Y; Cheng, Yan H; Cui, Jing; Oellerich, Thomas; Lenardo, Michael J.

Proc Natl Acad Sci U S A ; 119(33): e2208522119, 2022 08 16.

Artículo en Inglés | MEDLINE | ID: mdl-35939714

14.

Interim analysis: Open-label extension study of leniolisib for patients with APDS.

Rao, V Koneti; Kulm, Elaine; Sedivá, Anna; Plebani, Alessandro; Schuetz, Catharina; Shcherbina, Anna; Dalm, Virgil A; Trizzino, Antonino; Zharankova, Yulia; Webster, Sharon; Orpia, Alanvin; Körholz, Julia; Lougaris, Vassilios; Rodina, Yulia; Radford, Kath; Bradt, Jason; Relan, Anurag; Holland, Steven M; Lenardo, Michael J; Uzel, Gulbu.

J Allergy Clin Immunol ; 153(1): 265-274.e9, 2024 01.

Artículo en Inglés | MEDLINE | ID: mdl-37797893

15.

The prevalence and topography of spinal cord demyelination in multiple sclerosis: a retrospective study.

Waldman, Alex D; Catania, Cecilia; Pisa, Marco; Jenkinson, Mark; Lenardo, Michael J; DeLuca, Gabriele C.

Acta Neuropathol ; 147(1): 51, 2024 Mar 09.

Artículo en Inglés | MEDLINE | ID: mdl-38460050

16.

Homozygous IL37 mutation associated with infantile inflammatory bowel disease.

Zhang, Zinan Z; Zhang, Yu; He, Tingyan; Sweeney, Colin L; Baris, Safa; Karakoc-Aydiner, Elif; Yao, Yikun; Ertem, Deniz; Matthews, Helen F; Gonzaga-Jauregui, Claudia; Malech, Harry L; Su, Helen C; Ozen, Ahmet; Smith, Kenneth G C; Lenardo, Michael J.

Proc Natl Acad Sci U S A ; 118(10)2021 03 09.

Artículo en Inglés | MEDLINE | ID: mdl-33674380

17.

The kinase LRRK2 is a regulator of the transcription factor NFAT that modulates the severity of inflammatory bowel disease.

Liu, Zhihua; Lee, Jinwoo; Krummey, Scott; Lu, Wei; Cai, Huaibin; Lenardo, Michael J.

Nat Immunol ; 12(11): 1063-70, 2011 Oct 09.

Artículo en Inglés | MEDLINE | ID: mdl-21983832

18.

IKKß phosphorylation regulates RPS3 nuclear translocation and NF-κB function during infection with Escherichia coli strain O157:H7.

Wan, Fengyi; Weaver, Amanda; Gao, Xiaofei; Bern, Michael; Hardwidge, Philip R; Lenardo, Michael J.

Nat Immunol ; 12(4): 335-43, 2011 Apr.

Artículo en Inglés | MEDLINE | ID: mdl-21399639

19.

CRISPR-targeted MAGT1 insertion restores XMEN patient hematopoietic stem cells and lymphocytes.

Brault, Julie; Liu, Taylor; Bello, Ezekiel; Liu, Siyuan; Sweeney, Colin L; Meis, Ronald J; Koontz, Sherry; Corsino, Cristina; Choi, Uimook; Vayssiere, Guillaume; Bosticardo, Marita; Dowdell, Kennichi; Lazzarotto, Cicera R; Clark, Aaron B; Notarangelo, Luigi D; Ravell, Juan C; Lenardo, Michael J; Kleinstiver, Benjamin P; Tsai, Shengdar Q; Wu, Xiaolin; Dahl, Gary A; Malech, Harry L; De Ravin, Suk See.

Blood ; 138(26): 2768-2780, 2021 12 30.

Artículo en Inglés | MEDLINE | ID: mdl-34086870

20.

A different TIPE of immune homeostasis.

Freundt, Eric C; Bidere, Nicolas; Lenardo, Michael J.

Cell ; 133(3): 401-2, 2008 May 02.

Artículo en Inglés | MEDLINE | ID: mdl-18455981

Portal de Búsqueda de la BVS Ecuador

Información y Conocimiento para la Salud

Configurar filtros

Su selección (0)

Formato de exportación:

Exportar: